From real papers
to reviews you can verify
Ask a research question. LitSynth searches 125M+ papers, screens each one with a written reason, and drafts a literature review where every citation opens the source passage. It only cites papers you selected — nothing is invented.
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Papers, full text & metadata from
125M+ academic papers indexed · PubMed-focused search for biomedical questions
Why LitSynth
Chat AI is fast. Its citations aren't reliable.
A literature review is only as good as its references. Here is how LitSynth compares with the two ways researchers usually do it.
Where citations come from
Question → first draft
Search & screening record
Checking each claim
Deliverable
LitSynth produces a draft for expert review. It does not replace your academic judgement.
From question to draft
How a review gets made
Every run is a visible pipeline — what it searched, what it kept, and where each claim came from.
See the output first
This is what a LitSynth draft looks like
Every generated review is structured, cited from papers you selected, and audited claim by claim — so you know exactly what you get before you start.
3. GLP-1 receptor agonists and weight outcomes
Across the included trials, semaglutide 2.4 mg was consistently associated with clinically meaningful weight reduction versus placebo. The STEP 1 trial reported a mean change of −14.9% at 68 weeks[1]; sustained treatment in STEP 5 maintained −15.2% at two years[2]. Discontinuation was followed by substantial weight regain in the extension analysis[3], suggesting that treatment persistence is a key mediator of long-term outcomes.
Gastrointestinal adverse events were the most frequently reported safety signal across trials[1][4], though discontinuation rates remained below 7% in most study arms.
References (from your selected papers)
- [1] Wilding JPH, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021.
- [2] Garvey WT, et al. Two-year effects of semaglutide in adults with overweight or obesity (STEP 5). Nat Med. 2022.
- + 14 more selected papers…
Citation Audit
The audit checks each claim against your selected papers and flags anything with weak support — before you export.
View a full example review
Semaglutide for obesity: complete PRISMA-lite walkthrough
See real output
Read a full example before you sign up
Three public example reviews across medicine, education and public health — from the research question to the cited synthesis.
Medicine
Semaglutide for obesity
The full PRISMA-lite workflow, with screening notes and evidence tables.
Read the exampleEducation
AI in education
Research question framing, synthesis themes and citation audit notes.
Read the examplePublic health
Climate change and health
How a review is structured, from the question to evidence themes.
Read the exampleWhat LitSynth does not claim
Systematic Review Beta is PRISMA-lite: not full PRISMA 2020, no dual independent screening, no meta-analysis, no RoB 2 or GRADE. Every draft needs human review.
Support
FAQ
Frequently Asked Questions
LitSynth expands your research question into a retrieval strategy, finds relevant papers, screens them for fit, and drafts a structured literature review. The workflow keeps the search boundary, included papers, evidence excerpts, and citations visible so you can verify and edit the draft.
Your next literature review, with citations you can defend
Enter one research question and get a cited, auditable draft in minutes. Move to the stricter Systematic Review Beta only when you need it.
The free plan includes 30 credits a month — enough for one complete demo review.